(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Disintegrin and metalloproteinase domain-containing protein 10 Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Disintegrin and metalloproteinase domain-containing protein 17 Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Neutrophil collagenase Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Matrix metalloproteinase-9 Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Matrix metalloproteinase-14 Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Stromelysin-1 Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Interstitial collagenase Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Collagenase 3 Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	72 kDa type IV collagenase Protein (Entity type)	IC50
(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Matrilysin Protein (Entity type)	IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Disintegrin and metalloproteinase domain-containing protein 10
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Disintegrin and metalloproteinase domain-containing protein 17
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Neutrophil collagenase
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Matrix metalloproteinase-9
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Matrix metalloproteinase-14
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Stromelysin-1
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Interstitial collagenase
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Collagenase 3
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
72 kDa type IV collagenase
Protein (Entity type)
IC50

(R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Matrilysin
Protein (Entity type)
IC50

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