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Tosedostat (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Tosedostat's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Tosedostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.010508627
	Tosedostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGFBP5 Gene (Entity type)	-0.0060665645
	Tosedostat Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SKI II Compound (Entity type)	0.4520738422870636
	Tosedostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	-0.0053763334
	Tosedostat Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Puromycin-sensitive aminopeptidase Protein (Entity type)	IC50
	Tosedostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DDIT4 Gene (Entity type)	0.0074551404
	Tosedostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RELB Gene (Entity type)	0.006201059
	Tosedostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQSTM1 Gene (Entity type)	0.0092948135
	Tosedostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BNIP3 Gene (Entity type)	-0.005805929
	Tosedostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ALDOC Gene (Entity type)	-0.0059683835

Tosedostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
0.010508627

Tosedostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IGFBP5
Gene (Entity type)
-0.0060665645

Tosedostat
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SKI II
Compound (Entity type)
0.4520738422870636

Tosedostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
-0.0053763334

Tosedostat
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Puromycin-sensitive aminopeptidase
Protein (Entity type)
IC50

Tosedostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DDIT4
Gene (Entity type)
0.0074551404

Tosedostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RELB
Gene (Entity type)
0.006201059

Tosedostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQSTM1
Gene (Entity type)
0.0092948135

Tosedostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BNIP3
Gene (Entity type)
-0.005805929

Tosedostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ALDOC
Gene (Entity type)
-0.0059683835

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