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SLC4A4 (Gene)

Ensembl Gene ID: ENSG00000080493

Entrez Gene ID: 8671

Description: solute carrier family 4 member 4

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SLC4A4's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SLC4A4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SLC4A4.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SLC4A4.

Gene Sets (5077)

LINCS L1000 Chem Pert Consensus Sigs (1371)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1288)

A gene set library provided by LINCS

rummageo gene perturbations (145)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Aging Signatures 2021 (3)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (2000)

A gene set library provided by LINCS

rummageo chemical perturbations (254)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (4)

A gene set library provided by MoTrPAC

Genotype Tissue Expression

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	KU-C104233 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	0.015513302
	SID11111874 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	-0.003735225
	1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	0.0036552646
	SA-419090 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	0.012237751
	Antimycin-a Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	0.0053202156
	benzyl (S)-4-methyl-1-((S)-4-methyl-1-((S,E)-5-methyl-1-(methylsulfonyl)hex-1-en-3-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	-0.017738815
	1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	0.013134254
	Tosedostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	-0.0053763334
	JWE-035 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	-0.004760084
	Entecavir Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC4A4 Gene (Entity type)	-0.004685456

KU-C104233
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
0.015513302

SID11111874
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
-0.003735225

1-{2-[Bis-(4-trifluoromethyl-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
0.0036552646

SA-419090
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
0.012237751

Antimycin-a
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
0.0053202156

benzyl (S)-4-methyl-1-((S)-4-methyl-1-((S,E)-5-methyl-1-(methylsulfonyl)hex-1-en-3-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
-0.017738815

1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
0.013134254

Tosedostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
-0.0053763334

JWE-035
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
-0.004760084

Entecavir
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC4A4
Gene (Entity type)
-0.004685456

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.