N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IL6R Gene (Entity type)	-0.0034181755
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPCAM Gene (Entity type)	-0.0050017564
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASRGL1 Gene (Entity type)	-0.0035930972
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SORBS2 Gene (Entity type)	-0.0035227945
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HACD2 Gene (Entity type)	-0.003520542
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	-0.004561519
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT5 Gene (Entity type)	-0.0044781566
KIN001-127 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	0.3803445100784302
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FOLR1 Gene (Entity type)	-0.0049814084
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	-0.0034071307

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IL6R
Gene (Entity type)
-0.0034181755

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EPCAM
Gene (Entity type)
-0.0050017564

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASRGL1
Gene (Entity type)
-0.0035930972

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SORBS2
Gene (Entity type)
-0.0035227945

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HACD2
Gene (Entity type)
-0.003520542

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
-0.004561519

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT5
Gene (Entity type)
-0.0044781566

KIN001-127
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
0.3803445100784302

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FOLR1
Gene (Entity type)
-0.0049814084

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
-0.0034071307

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