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progesterone (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View progesterone's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	progesterone Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Endometrial Carcinoma Disease or Phenotype (Entity type)
	progesterone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.0052650487
	progesterone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	0.004265287
	progesterone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mineralocorticoid receptor Protein (Entity type)	Kd
	progesterone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cation channel sperm-associated protein 2 Protein (Entity type)	EC50
	progesterone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TLR4 Gene (Entity type)	-0.0031909454
	progesterone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FGFR3 Gene (Entity type)	-0.0035892965
	progesterone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TACSTD2 Gene (Entity type)	0.0041702287
	progesterone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASS1 Gene (Entity type)	0.004013488
	progesterone Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Progesterone receptor Protein (Entity type)	EC50

progesterone
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Endometrial Carcinoma
Disease or Phenotype (Entity type)

progesterone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.0052650487

progesterone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
0.004265287

progesterone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mineralocorticoid receptor
Protein (Entity type)
Kd

progesterone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cation channel sperm-associated protein 2
Protein (Entity type)
EC50

progesterone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TLR4
Gene (Entity type)
-0.0031909454

progesterone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FGFR3
Gene (Entity type)
-0.0035892965

progesterone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TACSTD2
Gene (Entity type)
0.0041702287

progesterone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASS1
Gene (Entity type)
0.004013488

progesterone
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Progesterone receptor
Protein (Entity type)
EC50

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