2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)'s neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NDRG1 Gene (Entity type)	-0.009204503
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	-0.010396873
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	JCHAIN Gene (Entity type)	0.008083309
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PGGHG Gene (Entity type)	-0.009679927
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT17 Gene (Entity type)	-0.009269105
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	10H-Phenoxazine Compound (Entity type)	0.3287668526172638
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	-0.015992926
2-(5-Methoxy-1H-indol-3-yl)-ethylamine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	0.3609998822212219
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TXNDC9 Gene (Entity type)	0.008033706
SID11113468 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin) Compound (Entity type)	0.2359115481376648

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NDRG1
Gene (Entity type)
-0.009204503

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
-0.010396873

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
JCHAIN
Gene (Entity type)
0.008083309

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PGGHG
Gene (Entity type)
-0.009679927

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT17
Gene (Entity type)
-0.009269105

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
10H-Phenoxazine
Compound (Entity type)
0.3287668526172638

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
-0.015992926

2-(5-Methoxy-1H-indol-3-yl)-ethylamine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
0.3609998822212219

2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TXNDC9
Gene (Entity type)
0.008033706

SID11113468
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)
Compound (Entity type)
0.2359115481376648

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.