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Crenolanib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Crenolanib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Crenolanib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-(2-(4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yloxy)ethyl)morpholine Compound (Entity type)	0.2729881107807159
	Crenolanib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP7 Gene (Entity type)	0.020359674
	Crenolanib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RNASE1 Gene (Entity type)	-0.024668397
	Crenolanib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Glycine--tRNA ligase Protein (Entity type)	Kd
	Crenolanib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-2 Gene (Entity type)	-0.02751443
	Crenolanib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GNAS Gene (Entity type)	-0.023266217
	Crenolanib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Platelet-derived growth factor receptor alpha Protein (Entity type)	Kd
	Crenolanib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DES Gene (Entity type)	0.026109984
	Crenolanib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SOX9 Gene (Entity type)	-0.023372479
	Crenolanib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	STK10 Gene (Entity type)	0.021015706

Crenolanib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-(2-(4-(2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yloxy)ethyl)morpholine
Compound (Entity type)
0.2729881107807159

Crenolanib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP7
Gene (Entity type)
0.020359674

Crenolanib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RNASE1
Gene (Entity type)
-0.024668397

Crenolanib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Glycine--tRNA ligase
Protein (Entity type)
Kd

Crenolanib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-2
Gene (Entity type)
-0.02751443

Crenolanib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GNAS
Gene (Entity type)
-0.023266217

Crenolanib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Platelet-derived growth factor receptor alpha
Protein (Entity type)
Kd

Crenolanib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DES
Gene (Entity type)
0.026109984

Crenolanib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SOX9
Gene (Entity type)
-0.023372479

Crenolanib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
STK10
Gene (Entity type)
0.021015706

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