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imatinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View imatinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	imatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1X Gene (Entity type)	-0.003328644
	imatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.005121116
	imatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Macrophage colony-stimulating factor 1 receptor Protein (Entity type)	Kd
	imatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DHCR24 Gene (Entity type)	0.0039825626
	imatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PHLDA2 Gene (Entity type)	0.0048222863
	N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	imatinib Compound (Entity type)	0.2855340838432312
	imatinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Ribosyldihydronicotinamide dehydrogenase [quinone] Protein (Entity type)	Ki
	imatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLU Gene (Entity type)	-0.0030783378
	imatinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Philadelphia Chromosome Positive Chronic Myelocytic Leukemia Disease or Phenotype (Entity type)
	imatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI27 Gene (Entity type)	-0.005224372

imatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1X
Gene (Entity type)
-0.003328644

imatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
0.005121116

imatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Macrophage colony-stimulating factor 1 receptor
Protein (Entity type)
Kd

imatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DHCR24
Gene (Entity type)
0.0039825626

imatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PHLDA2
Gene (Entity type)
0.0048222863

N-(5-(5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
imatinib
Compound (Entity type)
0.2855340838432312

imatinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Ribosyldihydronicotinamide dehydrogenase [quinone]
Protein (Entity type)
Ki

imatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLU
Gene (Entity type)
-0.0030783378

imatinib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia
Disease or Phenotype (Entity type)

imatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI27
Gene (Entity type)
-0.005224372

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