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MK-0677 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MK-0677's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	MK-0677 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	-0.004166206
	MK-0677 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL8 Gene (Entity type)	-0.004787955
	MK-0677 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PROM1 Gene (Entity type)	-0.0046863426
	MK-0677 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HACD1 Gene (Entity type)	-0.004257082
	1-(2,6-Dichloro-phenyl)-2-(2,4-dichloro-phenyl)-3-imidazol-1-yl-propan-2-ol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	MK-0677 Compound (Entity type)	0.325625330209732
	MK-0677 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TENT4A Gene (Entity type)	0.0047802245
	Solifenacin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	MK-0677 Compound (Entity type)	0.2654111683368683
	MK-0677 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LTF Gene (Entity type)	-0.0055612368
	MK-0677 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LYZ Gene (Entity type)	0.0066192676
	MK-0677 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RHOB Gene (Entity type)	-0.004282144

MK-0677
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
-0.004166206

MK-0677
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL8
Gene (Entity type)
-0.004787955

MK-0677
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PROM1
Gene (Entity type)
-0.0046863426

MK-0677
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HACD1
Gene (Entity type)
-0.004257082

1-(2,6-Dichloro-phenyl)-2-(2,4-dichloro-phenyl)-3-imidazol-1-yl-propan-2-ol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
MK-0677
Compound (Entity type)
0.325625330209732

MK-0677
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TENT4A
Gene (Entity type)
0.0047802245

Solifenacin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
MK-0677
Compound (Entity type)
0.2654111683368683

MK-0677
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LTF
Gene (Entity type)
-0.0055612368

MK-0677
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LYZ
Gene (Entity type)
0.0066192676

MK-0677
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RHOB
Gene (Entity type)
-0.004282144

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