PRKCQ (Gene)

Entrez Gene ID: 5588

Description: protein kinase C theta

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRKCQ's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PRKCQ.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRKCQ.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRKCQ.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRKCQ.

Gene Sets (2463)

LINCS L1000 Chem Pert Consensus Sigs (639)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (528)

A gene set library provided by LINCS

rummageo gene perturbations (131)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (287)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (648)

A gene set library provided by LINCS

rummageo chemical perturbations (208)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (6)

A gene set library provided by GTEx

IDG Drug Targets 2022 (6)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Atovaquone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	-0.005812039
MK-0677 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	-0.004166206
1-(2-Chloro-thiophen-3-yl)-2-(2,4-dichloro-phenyl)-3-imidazol-1-yl-propan-2-ol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	0.0056891628
Isoproterenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	0.018868022
NF-449 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	0.0037525354
SID11113806 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	-0.0039703213
mephenytoin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	0.0046552154
SR-33805 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	-0.0041369
OCO-1112 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	-0.0072415303
Ritonavir Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRKCQ Gene (Entity type)	-0.0067855534

Atovaquone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
-0.005812039

MK-0677
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
-0.004166206

1-(2-Chloro-thiophen-3-yl)-2-(2,4-dichloro-phenyl)-3-imidazol-1-yl-propan-2-ol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
0.0056891628

Isoproterenol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
0.018868022

NF-449
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
0.0037525354

SID11113806
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
-0.0039703213

mephenytoin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
0.0046552154

SR-33805
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
-0.0041369

OCO-1112
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
-0.0072415303

Ritonavir
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRKCQ
Gene (Entity type)
-0.0067855534

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.