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refametinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View refametinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	refametinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLPI Gene (Entity type)	0.0070817475
	refametinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFIT1 Gene (Entity type)	0.008066982
	refametinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TMEM158 Gene (Entity type)	-0.007644734
	refametinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLE2 Gene (Entity type)	-0.006598932
	Ro-4987655 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	refametinib Compound (Entity type)	0.7959343791007996
	refametinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPRY4 Gene (Entity type)	-0.006031766
	refametinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BST2 Gene (Entity type)	0.0069885594
	refametinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C2 Gene (Entity type)	0.0064174803
	binimetinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	refametinib Compound (Entity type)	0.7350967526435852
	refametinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP5 Gene (Entity type)	-0.0064255814

refametinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLPI
Gene (Entity type)
0.0070817475

refametinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IFIT1
Gene (Entity type)
0.008066982

refametinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TMEM158
Gene (Entity type)
-0.007644734

refametinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
POLE2
Gene (Entity type)
-0.006598932

Ro-4987655
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
refametinib
Compound (Entity type)
0.7959343791007996

refametinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPRY4
Gene (Entity type)
-0.006031766

refametinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BST2
Gene (Entity type)
0.0069885594

refametinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C2
Gene (Entity type)
0.0064174803

binimetinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
refametinib
Compound (Entity type)
0.7350967526435852

refametinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP5
Gene (Entity type)
-0.0064255814

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