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filgotinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View filgotinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	filgotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EDN3 Gene (Entity type)	-0.0050726724
	filgotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADGRG2 Gene (Entity type)	-0.005066256
	filgotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCG5 Gene (Entity type)	-0.0044721486
	filgotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.004448046
	filgotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS2 Gene (Entity type)	0.003674852
	filgotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	0.003698433
	filgotinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(S)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide Compound (Entity type)	0.3609053194522857
	filgotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LMO2 Gene (Entity type)	-0.004557294
	filgotinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP7 Gene (Entity type)	-0.0049041845
	filgotinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KIF20A Gene (Entity type)	0.0041210293

filgotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EDN3
Gene (Entity type)
-0.0050726724

filgotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADGRG2
Gene (Entity type)
-0.005066256

filgotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SCG5
Gene (Entity type)
-0.0044721486

filgotinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
0.004448046

filgotinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCS2
Gene (Entity type)
0.003674852

filgotinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
0.003698433

filgotinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(S)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-6-(oxetan-3-ylamino)pyrimidine-4-carboxamide
Compound (Entity type)
0.3609053194522857

filgotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LMO2
Gene (Entity type)
-0.004557294

filgotinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP7
Gene (Entity type)
-0.0049041845

filgotinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KIF20A
Gene (Entity type)
0.0041210293

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