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Ceritinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Ceritinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Ceritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPD1 Gene (Entity type)	-0.0057656425
	Ceritinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Non-Small Cell Lung Carcinoma Disease or Phenotype (Entity type)
	Ceritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI27 Gene (Entity type)	-0.0072774477
	Ceritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.010263591
	Ceritinib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Anaplastic lymphoma kinase fusion oncogene positive non-small cell lung cancer Disease or Phenotype (Entity type)
	Ceritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TPSB2 Gene (Entity type)	0.0064792503
	Ceritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LTF Gene (Entity type)	0.006066788
	Ceritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.009455444
	Ceritinib Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proto-oncogene tyrosine-protein kinase ROS Protein (Entity type)	Ki
	Ceritinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	P4HA2 Gene (Entity type)	-0.005166774

Ceritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPD1
Gene (Entity type)
-0.0057656425

Ceritinib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Non-Small Cell Lung Carcinoma
Disease or Phenotype (Entity type)

Ceritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI27
Gene (Entity type)
-0.0072774477

Ceritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.010263591

Ceritinib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Anaplastic lymphoma kinase fusion oncogene positive non-small cell lung cancer
Disease or Phenotype (Entity type)

Ceritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TPSB2
Gene (Entity type)
0.0064792503

Ceritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LTF
Gene (Entity type)
0.006066788

Ceritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IDI1
Gene (Entity type)
0.009455444

Ceritinib
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proto-oncogene tyrosine-protein kinase ROS
Protein (Entity type)
Ki

Ceritinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
P4HA2
Gene (Entity type)
-0.005166774

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