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monacolin K (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View monacolin K's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	monacolin K Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPM6B Gene (Entity type)	-0.006953699
	norgestimate Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	monacolin K Compound (Entity type)	0.3125430345535278
	monacolin K Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MX1 Gene (Entity type)	-0.006762642
	monacolin K Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Familial hypercholesterolemia - heterozygous Disease or Phenotype (Entity type)
	monacolin K Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	3-hydroxy-3-methylglutaryl-coenzyme A reductase Protein (Entity type)	Ki
	monacolin K Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MALL Gene (Entity type)	0.0068554482
	monacolin K Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFI6 Gene (Entity type)	-0.007834957
	monacolin K Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Arteriosclerosis Disease or Phenotype (Entity type)
	monacolin K Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C2 Gene (Entity type)	0.006731123
	monacolin K Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.008442334

monacolin K
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPM6B
Gene (Entity type)
-0.006953699

norgestimate
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
monacolin K
Compound (Entity type)
0.3125430345535278

monacolin K
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MX1
Gene (Entity type)
-0.006762642

monacolin K
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Familial hypercholesterolemia - heterozygous
Disease or Phenotype (Entity type)

monacolin K
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein (Entity type)
Ki

monacolin K
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MALL
Gene (Entity type)
0.0068554482

monacolin K
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFI6
Gene (Entity type)
-0.007834957

monacolin K
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Arteriosclerosis
Disease or Phenotype (Entity type)

monacolin K
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C2
Gene (Entity type)
0.006731123

monacolin K
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IDI1
Gene (Entity type)
0.008442334

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