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Nikethamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Nikethamide's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Nikethamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl]-phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol(probucol)::2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenol::CHEMBL608::DH-581::Lorelco::PROBUCOL::US9182402, 14 Compound (Entity type)	0.3852030038833618
	Nikethamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BBOX1 Gene (Entity type)	0.005345135
	Nikethamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SRGN Gene (Entity type)	0.004219287
	sertaconazole Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Nikethamide Compound (Entity type)	0.3971758782863617
	Nikethamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLXNB2 Gene (Entity type)	-0.00398196
	Nikethamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MLPH Gene (Entity type)	-0.0041740895
	Nikethamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CIAO3 Gene (Entity type)	0.006396591
	Nikethamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPNMB Gene (Entity type)	-0.0044475254
	Nikethamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	VDAC1 Gene (Entity type)	0.004464029
	Nikethamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPCN1 Gene (Entity type)	-0.0037383803

Nikethamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl]-phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol(probucol)::2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenol::CHEMBL608::DH-581::Lorelco::PROBUCOL::US9182402, 14
Compound (Entity type)
0.3852030038833618

Nikethamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BBOX1
Gene (Entity type)
0.005345135

Nikethamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SRGN
Gene (Entity type)
0.004219287

sertaconazole
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Nikethamide
Compound (Entity type)
0.3971758782863617

Nikethamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLXNB2
Gene (Entity type)
-0.00398196

Nikethamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MLPH
Gene (Entity type)
-0.0041740895

Nikethamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CIAO3
Gene (Entity type)
0.006396591

Nikethamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPNMB
Gene (Entity type)
-0.0044475254

Nikethamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
VDAC1
Gene (Entity type)
0.004464029

Nikethamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TPCN1
Gene (Entity type)
-0.0037383803

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