TP53 (Gene)

Description: tumor protein p53

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TP53's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TP53.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TP53.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TP53.

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Gene Sets (443)

LINCS L1000 Chem Pert Consensus Sigs (296)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (146)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
benzethonium Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	0.03906423
17-beta-estradiol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	-0.0025881124
Scriptaid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	-0.012081057
methoxamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	0.016572472
2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	-0.0056850174
Vorinostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	-0.011668403
Phenindione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	0.02082873
NCH-51 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	-0.013718835
HC-toxin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	-0.0198165
Pyroxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TP53 Gene (Entity type)	-0.0097923055