PRF1 (Gene)

Description: perforin 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PRF1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PRF1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PRF1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PRF1.

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Gene Sets (1245)

LINCS L1000 Chem Pert Consensus Sigs (567)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (6)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (658)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (12)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SR-33805 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	-0.004042392
Biotin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	0.008086351
mercaptopurine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	0.0039173164
lomatin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	0.0093731545
2-(2-chloro-4-fluorobenzyl)-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	-0.005849406
Null cell Anatomy (Entity type)	Has marker gene in heart Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)
Ifosfamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	0.0071600745
Linezolid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	-0.0028495833
Inositol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	0.008675546
Ganaxolone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRF1 Gene (Entity type)	-0.0051314407