PERP (Gene)

Description: p53 apoptosis effector related to PMP22

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PERP's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PERP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PERP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PERP.

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Gene Sets (3178)

LINCS L1000 Chem Pert Consensus Sigs (1350)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (10)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1804)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
RAN-03 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.009986889
JAS07-009 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.013406759
GW3965 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.011031696
2-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (quinapril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.0031503423
SID87457340 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.011646441
K-145 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.007762994
Clotrimazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.0062427106
3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	0.008688741
PF750 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.0057443352
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.009874801