HLA-DRB1 (Gene)

Description: major histocompatibility complex, class II, DR beta 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HLA-DRB1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HLA-DRB1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HLA-DRB1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HLA-DRB1.

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Gene Sets (610)

LINCS L1000 Chem Pert Consensus Sigs (355)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (247)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Kidney_L3_monocyte-derived dendritic cell Anatomy (Entity type)	Has marker gene in kidney Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)
PCA 4248 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	0.0033392992
N-{4-chloro-2-[(1-oxidopyridin-4-yl)carbonyl]phenyl}-4-(1,1-dimethylethyl)benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	0.004684399
Fenoldopam Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	0.0030101985
SID11113966 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	-0.004822438
Amlexanox Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	0.0049908487
methyl (3aR,4S,7aR)-4-hydroxy-4-[(3-methylphenyl)ethynyl]octahydro-1H-indole-1-carboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	0.005481951
3-[(R)-3-(4-Fluoro-benzenesulfonylamino)-1,2,3,4-tetrahydro-carbazol-9-yl]-propionic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	0.0031351922
cinoxacin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	0.0041281036
4-(4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl)-2-methoxypyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HLA-DRB1 Gene (Entity type)	-0.006771224