ARHGEF3 (Gene)

Description: Rho guanine nucleotide exchange factor 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ARHGEF3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ARHGEF3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ARHGEF3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ARHGEF3.

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Gene Sets (1476)

LINCS L1000 Chem Pert Consensus Sigs (750)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (718)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (6)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
eriodictyol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	-0.0063915676
Fomepizole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	-0.004046413
cobimetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	0.00652795
KFGENEBIN:ARHGEF3-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)
SID11112305 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	0.020886201
SA-90377 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	-0.0091643
L-glutamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	-0.0105433
tubocurarine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	0.0070682685
Oxiconazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	-0.006358679
Sotagliflozin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARHGEF3 Gene (Entity type)	0.005074721