WEE1 (Gene)

Description: WEE1 G2 checkpoint kinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View WEE1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with WEE1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using WEE1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for WEE1.

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Gene Sets (948)

LINCS L1000 Chem Pert Consensus Sigs (623)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (305)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (5)

A gene set library provided by GTEx

IDG Drug Targets 2022 (7)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	0.003416431
MK2a inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	-0.01015921
hippeastrine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	0.01006681
N-(1-Cyclohexylpiperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	-0.01554364
fisetinidol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	-0.0104758395
SA-1458902 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	0.017370138
Ixabepilone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	-0.00919474
Methysergide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	0.0050711124
JTC-801 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	0.004241133
BG-1023 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	0.0172138