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Tranilast (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Tranilast's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Tranilast Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Dermatitis, Atopic Disease or Phenotype (Entity type)
	Tranilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KCTD5 Gene (Entity type)	-0.0032061506
	Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WEE1 Gene (Entity type)	0.003416431
	Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.0047857007
	Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL12 Gene (Entity type)	0.0041768807
	Tranilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGR5 Gene (Entity type)	-0.0032437274
	Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CD40 Gene (Entity type)	0.0034734996
	Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DNAJA3 Gene (Entity type)	0.0042114183
	Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LMO2 Gene (Entity type)	0.0035684954
	Tranilast Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT1H Gene (Entity type)	0.0034204156

Tranilast
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Dermatitis, Atopic
Disease or Phenotype (Entity type)

Tranilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KCTD5
Gene (Entity type)
-0.0032061506

Tranilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
WEE1
Gene (Entity type)
0.003416431

Tranilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.0047857007

Tranilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL12
Gene (Entity type)
0.0041768807

Tranilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGR5
Gene (Entity type)
-0.0032437274

Tranilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CD40
Gene (Entity type)
0.0034734996

Tranilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DNAJA3
Gene (Entity type)
0.0042114183

Tranilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LMO2
Gene (Entity type)
0.0035684954

Tranilast
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT1H
Gene (Entity type)
0.0034204156

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