TIAM1 (Gene)

Description: TIAM Rac1 associated GEF 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TIAM1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TIAM1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TIAM1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TIAM1.

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Gene Sets (732)

LINCS L1000 Chem Pert Consensus Sigs (640)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (6)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (73)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	-0.015546594
imiloxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	-0.0051843342
beta-CAROTENE Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	-0.012509112
N-{4-[4-(Ethyl-heptyl-amino)-1-hydroxy-butyl]-phenyl}-methanesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	0.0033579888
diphenhydramine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	-0.011293762
VU-0403126 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	-0.0102181025
ODQ Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	0.009368565
retigabine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	0.0028795735
KFGENEBIN:TIAM1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)
emapunil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	-0.0030677512