5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLTB Gene (Entity type)	-0.01522855
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NEBL Gene (Entity type)	0.016024878
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NELL2 Gene (Entity type)	-0.01645122
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MXRA7 Gene (Entity type)	-0.014775117
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCL2 Gene (Entity type)	0.019801037
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIAM1 Gene (Entity type)	-0.015546594
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PEX11A Gene (Entity type)	-0.014469501
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPER1 Gene (Entity type)	-0.015612718
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	C2CD2 Gene (Entity type)	-0.015445513
5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PEG10 Gene (Entity type)	0.017633498

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CLTB
Gene (Entity type)
-0.01522855

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NEBL
Gene (Entity type)
0.016024878

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NELL2
Gene (Entity type)
-0.01645122

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MXRA7
Gene (Entity type)
-0.014775117

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCL2
Gene (Entity type)
0.019801037

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIAM1
Gene (Entity type)
-0.015546594

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PEX11A
Gene (Entity type)
-0.014469501

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPER1
Gene (Entity type)
-0.015612718

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
C2CD2
Gene (Entity type)
-0.015445513

5-(4-(Isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PEG10
Gene (Entity type)
0.017633498

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