PI3 (Gene)

Description: peptidase inhibitor 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PI3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PI3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PI3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PI3.

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Gene Sets (3280)

LINCS L1000 Chem Pert Consensus Sigs (1514)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1737)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (24)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID11112222 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	-0.009546134
AZD-6765 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.007255571
AS-601245 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.0074242735
Icosa-8,11,14-trienoic acid (2-hydroxy-ethyl)-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.004234853
BAM-7 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.010216619
PF750 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	-0.00501991
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	-0.0038776014
SID11112144 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.0034640445
KU-C104123 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.012566467
hemado Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	0.010570136