1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SRPX Gene (Entity type)	0.0033929017
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mitogen-activated protein kinase 9 Protein (Entity type)	Kd
emapunil Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	0.3435390889644623
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	-0.0038776014
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IPO13 Gene (Entity type)	0.003352239
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	THY1 Gene (Entity type)	0.0033487384
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLXNB2 Gene (Entity type)	0.003332125
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Epithelial discoidin domain-containing receptor 1 Protein (Entity type)	Kd
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIM14 Gene (Entity type)	0.0033359488
CGP7930 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	0.2692537605762481

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SRPX
Gene (Entity type)
0.0033929017

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mitogen-activated protein kinase 9
Protein (Entity type)
Kd

emapunil
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
0.3435390889644623

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PI3
Gene (Entity type)
-0.0038776014

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IPO13
Gene (Entity type)
0.003352239

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
THY1
Gene (Entity type)
0.0033487384

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLXNB2
Gene (Entity type)
0.003332125

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Epithelial discoidin domain-containing receptor 1
Protein (Entity type)
Kd

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIM14
Gene (Entity type)
0.0033359488

CGP7930
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
0.2692537605762481

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.