1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SRPX Gene (Entity type)	0.0033929017
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Mitogen-activated protein kinase 9 Protein (Entity type)	Kd
emapunil Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	0.3435390889644623
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PI3 Gene (Entity type)	-0.0038776014
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IPO13 Gene (Entity type)	0.003352239
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	THY1 Gene (Entity type)	0.0033487384
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLXNB2 Gene (Entity type)	0.003332125
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Epithelial discoidin domain-containing receptor 1 Protein (Entity type)	Kd
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIM14 Gene (Entity type)	0.0033359488
CGP7930 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea Compound (Entity type)	0.2692537605762481

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SRPX
Gene (Entity type)
0.0033929017

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Mitogen-activated protein kinase 9
Protein (Entity type)
Kd

emapunil
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
0.3435390889644623

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PI3
Gene (Entity type)
-0.0038776014

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IPO13
Gene (Entity type)
0.003352239

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
THY1
Gene (Entity type)
0.0033487384

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLXNB2
Gene (Entity type)
0.003332125

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Epithelial discoidin domain-containing receptor 1
Protein (Entity type)
Kd

1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIM14
Gene (Entity type)
0.0033359488

CGP7930
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea
Compound (Entity type)
0.2692537605762481

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Knowledge Graph Assertions

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