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ZNF277 (Gene)

Ensembl Gene ID: ENSG00000198839

Entrez Gene ID: 11179

Description: zinc finger protein 277

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ZNF277's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ZNF277.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ZNF277.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ZNF277.

Gene Sets (1140)

LINCS L1000 Chem Pert Consensus Sigs (322)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (331)

A gene set library provided by LINCS

rummageo gene perturbations (66)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (294)

A gene set library provided by LINCS

rummageo chemical perturbations (126)

A gene set library provided by LINCS

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Altanserin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	-0.0029436706
	Diphenylpyraline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	0.0062034773
	Cefprozil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	0.03310668
	Methyl 4-(6-{4-[(methoxycarbonyl)amino]phenyl}-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	0.014410955
	dactolisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	0.009827162
	GSK-2126458 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	0.010838244
	5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	0.013557875
	(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	0.0100018205
	KFGENEBIN:ZNF277-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)
	SA-1922932 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ZNF277 Gene (Entity type)	-0.009412583

Altanserin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
-0.0029436706

Diphenylpyraline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
0.0062034773

Cefprozil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
0.03310668

Methyl 4-(6-{4-[(methoxycarbonyl)amino]phenyl}-4-morpholin-4-yl-1Hpyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
0.014410955

dactolisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
0.009827162

GSK-2126458
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
0.010838244

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
0.013557875

(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
0.0100018205

KFGENEBIN:ZNF277-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)

SA-1922932
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ZNF277
Gene (Entity type)
-0.009412583

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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