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MBP (Gene)

Ensembl Gene ID: ENSG00000197971

Entrez Gene ID: 4155

Description: myelin basic protein

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MBP's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MBP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MBP.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MBP.

Gene Sets (3682)

LINCS L1000 Chem Pert Consensus Sigs (832)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (19)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (968)

A gene set library provided by LINCS

rummageo gene perturbations (269)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1185)

A gene set library provided by LINCS

rummageo chemical perturbations (390)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Genotype Tissue Expression

GTEx Tissues V8 2023 (17)

A gene set library provided by GTEx

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.0055001983
	SA-1462738 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	-0.013939605
	3-[2-(4-Benzenesulfinylmethyl-4-methoxy-piperidin-1-yl)-ethyl]-5-fluoro-1H-indole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	-0.0096108485
	methoxamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.01928363
	SA-1921996 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.016251678
	dihydroobliquin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.009668972
	Sotagliflozin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	-0.0046549095
	N-[2-(3,4-Dichloro-phenyl)-ethyl]-N,N',N'-trimethyl-ethane-1,2-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.007883977
	Entospletinib; 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.0049905246
	ampalex Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MBP Gene (Entity type)	0.0035858252

N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.0055001983

SA-1462738
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
-0.013939605

3-[2-(4-Benzenesulfinylmethyl-4-methoxy-piperidin-1-yl)-ethyl]-5-fluoro-1H-indole
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
-0.0096108485

methoxamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.01928363

SA-1921996
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.016251678

dihydroobliquin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.009668972

Sotagliflozin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
-0.0046549095

N-[2-(3,4-Dichloro-phenyl)-ethyl]-N,N',N'-trimethyl-ethane-1,2-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.007883977

Entospletinib; 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo[1,2-a]pyrazin-8-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.0049905246

ampalex
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MBP
Gene (Entity type)
0.0035858252

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.