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CFDE Workbench

IFNL3 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:282617, HGNC:18365, IFN-lambda-3, IFN-lambda-4, IFNL3, IL-28B, IL-28C, IL28B, IL28C, MIM:607402, NM_001346937, NM_172139, NP_001333866, NP_742151, interferon lambda 3
Omim:OMIM:607402
Id:ENSG00000197110
Hgnc:HGNC:18365
Entrez:282617
Ensembl:ENSG00000197110
Description:interferon lambda 3
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IFNL3's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with IFNL3.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IFNL3.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IFNL3.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IFNL3.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE206931 WDR5 inhibition WIN 8 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE150895 GSE150896 enzalutamide 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE111247 temozolomide LN-308 2 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE150895,GSE150896 0 V 1 ENZALUTAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE184784 FACT SUPT16H inhibition Activated natural killer cell therapy 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE221577 PIK3R1 knockout 3 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE142210 9 V 10 PANOBINOSTAT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE237216 STAT1 knockout RPMI-8226 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE228106 paclitaxel R1192 3 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE142210 11 V 7 PANOBINOSTAT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE206931 WDR5 inhibition WIN 8 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE150895 GSE150896 enzalutamide 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE111247 temozolomide LN-308 2 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE150895,GSE150896 0 V 1 ENZALUTAMIDE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE184784 FACT SUPT16H inhibition Activated natural killer cell therapy 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE221577 PIK3R1 knockout 3 v 5 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE142210 9 V 10 PANOBINOSTAT HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE237216 STAT1 knockout RPMI-8226 1 v 3 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE228106 paclitaxel R1192 3 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE142210 11 V 7 PANOBINOSTAT HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.