GSE221577 PIK3R1 knockout 3 v 5 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE221577_PIK3R1 knockout_3_v_5_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE221577_PIK3R1 knockout_3_v_5_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE221577_PIK3R1 knockout_3_v_5_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE221577_PIK3R1 knockout_3_v_5_human_up.

Results found

Linked to

	Label	Description
	ATF3 Gene (Entity type)	activating transcription factor 3
	CHI3L1 Gene (Entity type)	chitinase 3 like 1
	CSTA Gene (Entity type)	cystatin A
	HMGCS1 Gene (Entity type)	3-hydroxy-3-methylglutaryl-CoA synthase 1
	SCD Gene (Entity type)	stearoyl-CoA desaturase
	TFPI Gene (Entity type)	tissue factor pathway inhibitor
	SERPINE2 Gene (Entity type)	serpin family E member 2
	TXNDC9 Gene (Entity type)	thioredoxin domain containing 9
	IFITM1 Gene (Entity type)	interferon induced transmembrane protein 1
	SRGN Gene (Entity type)	serglycin

ATF3

Gene (Entity type)

activating transcription factor 3

CHI3L1

Gene (Entity type)

chitinase 3 like 1

CSTA

Gene (Entity type)

cystatin A

HMGCS1

Gene (Entity type)

3-hydroxy-3-methylglutaryl-CoA synthase 1

SCD

Gene (Entity type)

stearoyl-CoA desaturase

TFPI

Gene (Entity type)

tissue factor pathway inhibitor

SERPINE2

Gene (Entity type)

serpin family E member 2

TXNDC9

Gene (Entity type)

thioredoxin domain containing 9

IFITM1

Gene (Entity type)

interferon induced transmembrane protein 1

SRGN

Gene (Entity type)

serglycin

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.