PUF60 (Gene)

Entrez Gene ID: 22827

Description: poly(U) binding splicing factor 60

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PUF60's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PUF60.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PUF60.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PUF60.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PUF60.

Gene Sets (2355)

LINCS L1000 Chem Pert Consensus Sigs (1207)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1146)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
KFGENEBIN:PUF60-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)
Amoxicillin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	-0.011150216
SID11113786 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	0.00809855
terbutaline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	-0.011094552
STK-721917 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	0.0033742927
JAK3 inhibitor IV Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	-0.0042762943
eseroline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	-0.034023885
DAC-009 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	-0.012986016
3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	-0.009469898
Suvorexant Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PUF60 Gene (Entity type)	0.0033672242

KFGENEBIN:PUF60-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)

Amoxicillin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
-0.011150216

SID11113786
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
0.00809855

terbutaline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
-0.011094552

STK-721917
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
0.0033742927

JAK3 inhibitor IV
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
-0.0042762943

eseroline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
-0.034023885

DAC-009
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
-0.012986016

3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
-0.009469898

Suvorexant
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PUF60
Gene (Entity type)
0.0033672242

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.