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OXCT1 (Gene)

Ensembl Gene ID: ENSG00000083720

Entrez Gene ID: 5019

Description: 3-oxoacid CoA-transferase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View OXCT1's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with OXCT1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using OXCT1.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for OXCT1.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	OXCT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Succinic Acid Metabolite (Entity type)
	OXCT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	succinic acid Metabolite (Entity type)
	2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	OXCT1 Gene (Entity type)	0.010247998
	istradefylline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	OXCT1 Gene (Entity type)	-0.0043588146
	OXCT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	succinyl-coenzyme A Metabolite (Entity type)
	TUL_XIX002 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	OXCT1 Gene (Entity type)	-0.012992724
	KFGENEBIN:OXCT1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	OXCT1 Gene (Entity type)
	OXCT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Acetoacetic acid Metabolite (Entity type)
	OXCT1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	acetoacetyl CoA Metabolite (Entity type)
	centpropazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	OXCT1 Gene (Entity type)	-0.004127295

OXCT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Succinic Acid
Metabolite (Entity type)

OXCT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
succinic acid
Metabolite (Entity type)

2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,Ndimethylbenzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
OXCT1
Gene (Entity type)
0.010247998

istradefylline
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
OXCT1
Gene (Entity type)
-0.0043588146

OXCT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
succinyl-coenzyme A
Metabolite (Entity type)

TUL_XIX002
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
OXCT1
Gene (Entity type)
-0.012992724

KFGENEBIN:OXCT1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
OXCT1
Gene (Entity type)

OXCT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Acetoacetic acid
Metabolite (Entity type)

OXCT1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
acetoacetyl CoA
Metabolite (Entity type)

centpropazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
OXCT1
Gene (Entity type)
-0.004127295

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