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UBR7 (Gene)

Ensembl Gene ID: ENSG00000012963

Entrez Gene ID: 55148

Description: ubiquitin protein ligase E3 component n-recognin 7

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View UBR7's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with UBR7.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using UBR7.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for UBR7.

Gene Sets (1463)

LINCS L1000 Chem Pert Consensus Sigs (345)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (325)

A gene set library provided by LINCS

rummageo gene perturbations (184)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (338)

A gene set library provided by LINCS

rummageo chemical perturbations (271)

A gene set library provided by LINCS

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	7-(2-(2-(dimethylamino)ethoxy)ethoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	0.0051750126
	I-303059 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	0.008746201
	Ergometrine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	0.010489754
	CCCP Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	0.007668627
	2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	-0.023867644
	(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	0.006224165
	KFGENEBIN:UBR7-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)
	Benproperine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	-0.01254706
	SA-1463839 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	UBR7 Gene (Entity type)	0.009375656

7-(2-(2-(dimethylamino)ethoxy)ethoxy)-6-methoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
0.0051750126

I-303059
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
0.008746201

Ergometrine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
0.010489754

CCCP
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
0.007668627

2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
-0.023867644

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
0.006224165

KFGENEBIN:UBR7-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)

Benproperine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
-0.01254706

SA-1463839
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
UBR7
Gene (Entity type)
0.009375656

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.