RRM2 (Gene)

Description: ribonucleotide reductase regulatory subunit M2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View RRM2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RRM2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using RRM2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for RRM2.

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Gene Sets (1560)

LINCS L1000 Chem Pert Consensus Sigs (1065)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (3)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (462)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (16)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (3)

A gene set library provided by GTEx

IDG Drug Targets 2022 (5)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
I-505056 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	-0.015286166
10,13-Dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.009275497
KU-C104486 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	-0.015839726
cercosporin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	-0.012850599
Meloxicam Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.0038911188
Acetazolamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.004187286
N-(2-aminoethyl)-4-chlorobenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.008715855
4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.013325974
enoxacin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.0031410719
salsolinol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRM2 Gene (Entity type)	0.007261824