SERPINB3 (Gene)

Description: serpin family B member 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SERPINB3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SERPINB3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SERPINB3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SERPINB3.

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Gene Sets (1636)

LINCS L1000 Chem Pert Consensus Sigs (710)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (897)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (12)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SA-1472514 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	-0.012589884
felamidin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	0.01342162
isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	-0.0046179765
SA-243193 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	-0.017196558
Duvelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	0.007458607
2-[2-(1-Carboxy-3-phenyl-propylamino)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (quinapril) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	0.0029710724
KFGENEBIN:SERPINB3-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)
tetraethyl 2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyldiphosphonate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	0.015037085
Didanosine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	0.009188533
cinchonine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB3 Gene (Entity type)	0.004469356