DTL (Gene)

Description: denticleless E3 ubiquitin protein ligase homolog

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DTL's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DTL.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DTL.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DTL.

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Gene Sets (923)

LINCS L1000 Chem Pert Consensus Sigs (598)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (311)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (8)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
fluoropyruvate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	0.005722933
cobimetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	-0.0075117755
Volasertib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	-0.010961992
metoprolol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	0.0034213169
SD-6-035-B4 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	0.007880606
Flutrimazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	0.0041013854
SID11112614 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	-0.012205091
Epothilone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	-0.011653765
2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	-0.005631497
SID11113976 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DTL Gene (Entity type)	-0.016402455