HSD11B2 (Gene)

Description: hydroxysteroid 11-beta dehydrogenase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HSD11B2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HSD11B2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HSD11B2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HSD11B2.

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Gene Sets (1232)

LINCS L1000 Chem Pert Consensus Sigs (492)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (704)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (9)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (9)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (8)

A gene set library provided by GTEx

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
HSD11B2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Corticosterone Metabolite (Entity type)
kidney connecting tubule principal cell Anatomy (Entity type)	Has marker gene in kidney Knowledge Graph Relation (Entity type)	HSD11B2 Gene (Entity type)
Nifenazone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B2 Gene (Entity type)	0.019370317
KM-03439 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B2 Gene (Entity type)	0.010459755
HSD11B2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	11-dehydrocorticosterone Metabolite (Entity type)
imidazolidinyl-urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSD11B2 Gene (Entity type)	0.019918812
HSD11B2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nadide Metabolite (Entity type)
HSD11B2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	cortisone Metabolite (Entity type)
HSD11B2 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nicotinamide adenine dinucleotide (NAD) Metabolite (Entity type)
KFGENEBIN:HSD11B2-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	HSD11B2 Gene (Entity type)