DUOX2 (Gene)

Description: dual oxidase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DUOX2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DUOX2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DUOX2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DUOX2.

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Gene Sets (1497)

LINCS L1000 Chem Pert Consensus Sigs (796)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (4)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (31)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (650)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (5)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (10)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
10H-Phenoxazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	0.0062906197
Methyllycaconitine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	0.008911619
N-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	0.0026983148
edrophonium Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	-0.0098422365
7-methyl-2-morpholino-9-(1-(phenylamino)ethyl)-4H-pyrido[1,2-a]pyrimidin-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	-0.0040526744
Iodixanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	-0.021747012
vancomycin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	0.018714765
AZD7545 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	0.00307049
Parecoxib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	0.015613988
tremorine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUOX2 Gene (Entity type)	-0.0072284155