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AZD7545 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AZD7545's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	AZD7545 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	VGLL4 Gene (Entity type)	-0.0033712501
	AZD7545 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FABP4 Gene (Entity type)	0.003535853
	AZD7545 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DLK1 Gene (Entity type)	0.0038677359
	AZD7545 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRS1 Gene (Entity type)	0.0029728403
	AZD7545 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DRAM1 Gene (Entity type)	-0.003230126
	AZD7545 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	[Pyruvate dehydrogenase Protein (Entity type)	IC50
	AZD7545 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PEG3 Gene (Entity type)	0.0030381102
	AZD7545 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	G0S2 Gene (Entity type)	0.0034620252
	AZD7545 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIRPA Gene (Entity type)	-0.0028207654
	AZD7545 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	H1-0 Gene (Entity type)	-0.0031792144

AZD7545
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
VGLL4
Gene (Entity type)
-0.0033712501

AZD7545
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FABP4
Gene (Entity type)
0.003535853

AZD7545
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DLK1
Gene (Entity type)
0.0038677359

AZD7545
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRS1
Gene (Entity type)
0.0029728403

AZD7545
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DRAM1
Gene (Entity type)
-0.003230126

AZD7545
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
[Pyruvate dehydrogenase
Protein (Entity type)
IC50

AZD7545
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PEG3
Gene (Entity type)
0.0030381102

AZD7545
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
G0S2
Gene (Entity type)
0.0034620252

AZD7545
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIRPA
Gene (Entity type)
-0.0028207654

AZD7545
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
H1-0
Gene (Entity type)
-0.0031792144

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