MKNK2 (Gene)

Description: MAPK interacting serine/threonine kinase 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MKNK2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MKNK2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MKNK2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MKNK2.

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Gene Sets (1458)

LINCS L1000 Chem Pert Consensus Sigs (724)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (7)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (703)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (7)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (5)

A gene set library provided by GTEx

IDG Drug Targets 2022 (12)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
cytosporone B Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	-0.0070239846
Blebbistatin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	0.007729424
KFGENEBIN:MKNK2-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)
Quercetagetin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	-0.007852928
dexloxiglumide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	-0.008172854
SID11113496 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	0.009138378
Tegaserod Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	0.017313337
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	-0.012740041
N-hydroxybenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	-0.005557646
lorazepam Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MKNK2 Gene (Entity type)	-0.0033272563