2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KCTD12 Gene (Entity type)	0.013212206
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SELENOP Gene (Entity type)	0.013313567
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	P4HB Gene (Entity type)	-0.014357765
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DNAJA3 Gene (Entity type)	-0.01647731
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Protein-serine O-palmitoleoyltransferase porcupine Protein (Entity type)	IC50
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	ME-0328 Compound (Entity type)	0.4842979907989502
hydroxyurea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	0.3697647452354431
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	0.01359907
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	F2RL1 Gene (Entity type)	0.017199188
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TM4SF1 Gene (Entity type)	0.014692664

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KCTD12
Gene (Entity type)
0.013212206

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SELENOP
Gene (Entity type)
0.013313567

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
P4HB
Gene (Entity type)
-0.014357765

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DNAJA3
Gene (Entity type)
-0.01647731

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Protein-serine O-palmitoleoyltransferase porcupine
Protein (Entity type)
IC50

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
ME-0328
Compound (Entity type)
0.4842979907989502

hydroxyurea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
0.3697647452354431

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
0.01359907

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
F2RL1
Gene (Entity type)
0.017199188

2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TM4SF1
Gene (Entity type)
0.014692664

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.