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Proton-coupled folate transporter (Protein)

Description: A protein in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Proton-coupled folate transporter 's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(4-(3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)propyl)-2-fluorobenzoyl)-L-glutamic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	pralatrexate Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	(S)-2-(5-(4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)thiophene-2-carboxamido)pentanedioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	{4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethoxy]benzoyl}-L-glutamic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	(2S)-2-[[4-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)butyl]benzoyl]amino]pentanedioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	(4-(3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)propyl)-3-fluorothiophene-2-carbonyl)-L-glutamic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	(S)-2-(4-(4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)thiophene-2-carboxamido)pentanedioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	(S)-2-(5-(3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl)thiophene-2-carboxamido)pentanedioic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	(4-(4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)-3-fluorobenzoyl)-L-glutamic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50
	(S)-2-({5-[3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)-propyl]-thiophene-3-carbonyl}-amino)-pentanedioic Acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Proton-coupled folate transporter Protein (Entity type)	IC50

(4-(3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)propyl)-2-fluorobenzoyl)-L-glutamic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

pralatrexate
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

(S)-2-(5-(4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)thiophene-2-carboxamido)pentanedioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

{4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)ethoxy]benzoyl}-L-glutamic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

(2S)-2-[[4-[4-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-6-yl)butyl]benzoyl]amino]pentanedioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

(4-(3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)propyl)-3-fluorothiophene-2-carbonyl)-L-glutamic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

(S)-2-(4-(4-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)thiophene-2-carboxamido)pentanedioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

(S)-2-(5-(3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)propyl)thiophene-2-carboxamido)pentanedioic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

(4-(4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl)-3-fluorobenzoyl)-L-glutamic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

(S)-2-({5-[3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)-propyl]-thiophene-3-carbonyl}-amino)-pentanedioic Acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Proton-coupled folate transporter
Protein (Entity type)
IC50

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