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Physostigmine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Physostigmine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Physostigmine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	-0.004261365
	Physostigmine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CA2 Gene (Entity type)	0.0033607485
	Physostigmine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IER5 Gene (Entity type)	-0.0027824133
	Physostigmine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	hydrazinecarboximidamide Compound (Entity type)	0.4163922071456909
	Physostigmine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINA1 Gene (Entity type)	0.0030239907
	Physostigmine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FXR1 Gene (Entity type)	-0.002602104
	Physostigmine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPB8 Gene (Entity type)	0.0035847528
	Physostigmine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide::CHEMBL551466::US9333195, 44 Compound (Entity type)	0.3662954270839691
	Physostigmine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	0.0030133363
	Physostigmine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A7 Gene (Entity type)	-0.003053141

Physostigmine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ATF3
Gene (Entity type)
-0.004261365

Physostigmine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CA2
Gene (Entity type)
0.0033607485

Physostigmine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IER5
Gene (Entity type)
-0.0027824133

Physostigmine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
hydrazinecarboximidamide
Compound (Entity type)
0.4163922071456909

Physostigmine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINA1
Gene (Entity type)
0.0030239907

Physostigmine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FXR1
Gene (Entity type)
-0.002602104

Physostigmine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPB8
Gene (Entity type)
0.0035847528

Physostigmine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide::CHEMBL551466::US9333195, 44
Compound (Entity type)
0.3662954270839691

Physostigmine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
0.0030133363

Physostigmine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A7
Gene (Entity type)
-0.003053141

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