GRIA2 (Gene)

Ensembl Gene ID: ENSG00000120251

Entrez Gene ID: 2891

Description: glutamate ionotropic receptor AMPA type subunit 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GRIA2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GRIA2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GRIA2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GRIA2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GRIA2.

Gene Sets (5156)

LINCS L1000 Chem Pert Consensus Sigs (1480)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (37)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (4)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1340)

A gene set library provided by LINCS

rummageo gene perturbations (46)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (18)

A gene set library provided by GTEx

RummaGEO DrugPerturbations 2025 (83)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (2087)

A gene set library provided by LINCS

rummageo chemical perturbations (54)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (5)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
STK-674938 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.010280979
gabapentin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.0038157143
VU-0415108-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.014501725
sphinganine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	0.0043971594
Reserpic-acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.0124618225
VU-0415012 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.016780645
RVX 208 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	0.0071978206
[3-(1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenoxy]-acetic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.008247143
PATI-1-2-3 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.01596668
SA-1459256 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GRIA2 Gene (Entity type)	-0.016557537

STK-674938
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.010280979

gabapentin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.0038157143

VU-0415108-1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.014501725

sphinganine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
0.0043971594

Reserpic-acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.0124618225

VU-0415012
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.016780645

RVX 208
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
0.0071978206

[3-(1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenoxy]-acetic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.008247143

PATI-1-2-3
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.01596668

SA-1459256
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GRIA2
Gene (Entity type)
-0.016557537

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.