1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.006043423
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCK2 Gene (Entity type)	0.0043629245
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LSS Gene (Entity type)	0.005372501
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CD93 Gene (Entity type)	-0.003500768
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	-0.0037156534
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.0040192916
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A9 Gene (Entity type)	-0.004185849
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYCBP Gene (Entity type)	-0.0032769714
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.009938581
Demecarium Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	0.1787539720535278

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IDI1
Gene (Entity type)
0.006043423

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCK2
Gene (Entity type)
0.0043629245

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LSS
Gene (Entity type)
0.005372501

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CD93
Gene (Entity type)
-0.003500768

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
APOD
Gene (Entity type)
-0.0037156534

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.0040192916

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A9
Gene (Entity type)
-0.004185849

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MYCBP
Gene (Entity type)
-0.0032769714

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.009938581

Demecarium
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
0.1787539720535278

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