1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDI1 Gene (Entity type)	0.006043423
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PCK2 Gene (Entity type)	0.0043629245
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LSS Gene (Entity type)	0.005372501
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CD93 Gene (Entity type)	-0.003500768
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APOD Gene (Entity type)	-0.0037156534
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.0040192916
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A9 Gene (Entity type)	-0.004185849
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MYCBP Gene (Entity type)	-0.0032769714
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.009938581
Demecarium Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	0.1787539720535278

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IDI1
Gene (Entity type)
0.006043423

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PCK2
Gene (Entity type)
0.0043629245

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LSS
Gene (Entity type)
0.005372501

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CD93
Gene (Entity type)
-0.003500768

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
APOD
Gene (Entity type)
-0.0037156534

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.0040192916

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A9
Gene (Entity type)
-0.004185849

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MYCBP
Gene (Entity type)
-0.0032769714

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.009938581

Demecarium
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
0.1787539720535278

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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