7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
SID11110946 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	0.1920399218797683
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DUSP5 Gene (Entity type)	-0.010722668
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SELENOP Gene (Entity type)	0.014903667
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CP Gene (Entity type)	0.008521146
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADAM28 Gene (Entity type)	0.008396671
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MXI1 Gene (Entity type)	-0.00798596
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TGFBI Gene (Entity type)	-0.009496825
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CCNG2 Gene (Entity type)	-0.008159805
KM-03439 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	0.2452193200588226
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50

SID11110946
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
0.1920399218797683

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DUSP5
Gene (Entity type)
-0.010722668

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SELENOP
Gene (Entity type)
0.014903667

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CP
Gene (Entity type)
0.008521146

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADAM28
Gene (Entity type)
0.008396671

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MXI1
Gene (Entity type)
-0.00798596

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TGFBI
Gene (Entity type)
-0.009496825

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CCNG2
Gene (Entity type)
-0.008159805

KM-03439
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
0.2452193200588226

7-n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

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