Cystic fibrosis transmembrane conductance regulator (Protein)

Description: A protein in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Cystic fibrosis transmembrane conductance regulator 's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-2-(3-Cyclohexyloxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-pentyl-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50
(R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-butoxy-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50
4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid(4-tert-Butyl-3-aminophenyl)amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50
4-(4-(diethylamino)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazin-2-ylamino)benzoic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50
(R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-butyl-phenyl)-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50
N-(3-carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-4-chloro-5-methyl-1H-pyrazole-3-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50
6-(5-methyl-furan-2-yl)-7,9-dimethyl-11-phenyl-6,7-dihydro-5-oxa-7,9,11a-triaza-benzo[a]fluorene-8,10-dione Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	IC50
N-(4-nitro-2-(5-oxo-2,3-dihydro-5H-[1,4]oxazino[4,3,2-de]-quinoxalin-6-yl)phenyl)acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50
(R)-6-(5-Bromo-furan-2-yl)-7,9-dimethyl-8,10-dioxo-11-phenyl-7,8,9,10-tetrahydro-6H-5-oxa-7,9,11a-triazabenzo[a]fluorene-2-carboxylateisopropyl-ammonium Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	IC50
(R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [4-(acetyl-butyl-amino)-phenyl]-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cystic fibrosis transmembrane conductance regulator Protein (Entity type)	EC50

(S)-2-(3-Cyclohexyloxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-pentyl-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

(R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-butoxy-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid(4-tert-Butyl-3-aminophenyl)amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

4-(4-(diethylamino)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazin-2-ylamino)benzoic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

(R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid (4-butyl-phenyl)-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

N-(3-carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-2-yl)-4-chloro-5-methyl-1H-pyrazole-3-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

6-(5-methyl-furan-2-yl)-7,9-dimethyl-11-phenyl-6,7-dihydro-5-oxa-7,9,11a-triaza-benzo[a]fluorene-8,10-dione
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
IC50

N-(4-nitro-2-(5-oxo-2,3-dihydro-5H-[1,4]oxazino[4,3,2-de]-quinoxalin-6-yl)phenyl)acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

(R)-6-(5-Bromo-furan-2-yl)-7,9-dimethyl-8,10-dioxo-11-phenyl-7,8,9,10-tetrahydro-6H-5-oxa-7,9,11a-triazabenzo[a]fluorene-2-carboxylateisopropyl-ammonium
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
IC50

(R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid [4-(acetyl-butyl-amino)-phenyl]-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cystic fibrosis transmembrane conductance regulator
Protein (Entity type)
EC50

DISPLAY PER PAGE

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.