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Duloxetine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Duloxetine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Duloxetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BAD Gene (Entity type)	-0.0034656601
	Duloxetine Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Fibromyalgia Disease or Phenotype (Entity type)
	Duloxetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRTN3 Gene (Entity type)	-0.0037879918
	Duloxetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.0048797224
	Duloxetine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDH2 Gene (Entity type)	0.0035715972
	Duloxetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RTN2 Gene (Entity type)	-0.0037362196
	Duloxetine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CES1 Gene (Entity type)	0.0036355737
	Duloxetine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Cytochrome P450 2D6 Protein (Entity type)	IC50
	Duloxetine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.0036228723
	Duloxetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	FAM13A Gene (Entity type)	-0.0032475954

Duloxetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BAD
Gene (Entity type)
-0.0034656601

Duloxetine
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Fibromyalgia
Disease or Phenotype (Entity type)

Duloxetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PRTN3
Gene (Entity type)
-0.0037879918

Duloxetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.0048797224

Duloxetine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDH2
Gene (Entity type)
0.0035715972

Duloxetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RTN2
Gene (Entity type)
-0.0037362196

Duloxetine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CES1
Gene (Entity type)
0.0036355737

Duloxetine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Cytochrome P450 2D6
Protein (Entity type)
IC50

Duloxetine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
0.0036228723

Duloxetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
FAM13A
Gene (Entity type)
-0.0032475954

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