TIMM22 (Gene)

Entrez Gene ID: 29928

Description: translocase of inner mitochondrial membrane 22

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TIMM22's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TIMM22.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TIMM22.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TIMM22.

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Gene Sets (2901)

LINCS L1000 Chem Pert Consensus Sigs (550)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1649)

A gene set library provided by LINCS

rummageo gene perturbations (96)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (507)

A gene set library provided by LINCS

rummageo chemical perturbations (91)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Golvatinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.004381789
6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.0036198115
Duloxetine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.0048797224
1-(3,4-dichlorophenethyl)-4-methylpiperazine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	0.0074644703
thenoyltrifluoroacetone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.007875265
CGS-21680 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.0048716757
Alrestatin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.005115054
R-112 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	0.010975911
Losmapimod Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.0039705406
Vernakalant Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TIMM22 Gene (Entity type)	-0.005716159

Golvatinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.004381789

6-[(3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.0036198115

Duloxetine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.0048797224

1-(3,4-dichlorophenethyl)-4-methylpiperazine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
0.0074644703

thenoyltrifluoroacetone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.007875265

CGS-21680
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.0048716757

Alrestatin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.005115054

R-112
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
0.010975911

Losmapimod
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.0039705406

Vernakalant
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TIMM22
Gene (Entity type)
-0.005716159

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.