2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT1E Gene (Entity type)	0.01078373
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	KM-03949SC Compound (Entity type)	0.2123860120773315
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFF3 Gene (Entity type)	0.010916592
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	CGP53353 Compound (Entity type)	0.2381511479616165
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RRAGD Gene (Entity type)	0.0089838365
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Gastrin/cholecystokinin type B receptor Protein (Entity type)	IC50
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MSMO1 Gene (Entity type)	-0.008539495
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	0.008815626
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TUBB2B Gene (Entity type)	0.009237079
2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MT1H Gene (Entity type)	0.008444939

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT1E
Gene (Entity type)
0.01078373

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
KM-03949SC
Compound (Entity type)
0.2123860120773315

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFF3
Gene (Entity type)
0.010916592

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
CGP53353
Compound (Entity type)
0.2381511479616165

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RRAGD
Gene (Entity type)
0.0089838365

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Gastrin/cholecystokinin type B receptor
Protein (Entity type)
IC50

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MSMO1
Gene (Entity type)
-0.008539495

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
0.008815626

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TUBB2B
Gene (Entity type)
0.009237079

2-[2-(5-Bromo-1H-indol-3-yl)-ethyl]-3-(3-isopropoxy-phenyl)-3H-quinazolin-4-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MT1H
Gene (Entity type)
0.008444939

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.